Pednisol 5 | Prednisolone | Drug International Ltd.
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Home Medicines Allergies Pednisol 5 | 1 Strip

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Pednisol 5 | 1 Strip

Generic: Prednisolone

Type: Tablet

Pack Size: 10 Pcs

Prednisolone is a synthetic adrenocortical steroid with strong glucocorticoid activity and minimal mineralocorticoid effects.

  • Mechanism: Inhibits phospholipase A₂, reducing inflammatory mediators like leukotrienes, prostaglandins, and SRS-A.
  • Absorption: Rapid and complete oral absorption.
  • Protein binding: 70–90% in plasma.
  • Half-life: 2–4 hours.
  • Metabolism: Primarily hepatic; excreted via urine.
  1. Use only if benefits outweigh potential risks.
  2. Passes into breast milk; may affect infant growth and adrenal function.

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✅ Description:

Pednisol is prescribed for a wide range of inflammatory, autoimmune, allergic, and endocrine conditions:

  • Rheumatic disorders: Psoriatic arthritis, rheumatoid arthritis (including juvenile type), ankylosing spondylitis, acute/subacute bursitis, acute nonspecific tenosynovitis, acute gouty arthritis, post-traumatic osteoarthritis.
  • Endocrine disorders: Primary/secondary adrenocortical insufficiency, congenital adrenal hyperplasia, nonsuppurative thyroiditis, hypercalcemia associated with cancer.
  • Dermatologic diseases: Pemphigus, bullous dermatitis herpetiformis, severe erythema multiforme, exfoliative dermatitis, mycosis fungoides, severe psoriasis.
  • Allergic states: Seasonal/perennial allergic rhinitis, bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness, drug hypersensitivity reactions.
  • Respiratory diseases: Symptomatic sarcoidosis, berylliosis, and fulminating/aspiration pneumonitis.
  • Hematologic disorders: Idiopathic thrombocytopenic purpura, secondary thrombocytopenia, autoimmune hemolytic anemia, erythroblastopenia (RBC anemia).
  • Edematous states: Induction of diuresis/remission of proteinuria in nephrotic syndrome without uremia (idiopathic or lupus-related).
  • Gastrointestinal diseases: Ulcerative colitis, regional enteritis.
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✔️ Side Effects: Prednisolone

Fluid/electrolyte: Sodium/fluid retention, potassium loss, hypertension, CHF in predisposed patients.

Musculoskeletal: Weakness, osteoporosis, aseptic necrosis, fractures.

GI: Peptic ulcer, GI bleeding, pancreatitis.

Dermatologic: Fragile skin, poor wound healing, petechiae, erythema.

Neurological: Headache, vertigo, pseudotumor cerebri, seizures.

Endocrine: Cushingoid features, growth suppression, menstrual irregularities, glucose intolerance.

Ophthalmic: Cataracts, glaucoma, exophthalmos.

Metabolic: Negative nitrogen balance.

✔️ Dosage & Administration | Prednisolone

Adults

Nephrotic syndrome:

Initial: 2 mg/kg/day (max 80 mg/day) in 3–4 divided doses until proteinuria resolves for 3 consecutive days (max 28 days).

Then: 1–1.5 mg/kg every other day for 4 weeks.

Maintenance: 0.5–1 mg/kg every other day for 3–6 months.

Anti-inflammatory: 5–60 mg/day in 1–4 divided doses.

Acute asthma: 40–60 mg/day PO (single or divided) for 3–10 days.

Allergic conditions (tapering regimen):

Day 1: 10 mg (before breakfast), 5 mg (after lunch & dinner), 10 mg (bedtime)

Gradual dose reduction until Day 6: 5 mg (morning only).

Pediatrics

Asthma (Acute/Maintenance):

1 year: 10 mg q12h / every other day

1–4 years: 20 mg q12h / every other day

5–12 years: 30 mg q12h / every other day

≥12 years: 40 mg q12h / every other day

Anti-inflammatory / Immunosuppression: 0.05–2 mg/kg/day in 1–4 divided doses.

✔️ Interaction

Reduced efficacy with aminoglutethimide, antacids, barbiturates, carbamazepine, griseofulvin, mitotane, phenylbutazone, phenytoin, primidone, and rifampin.

Risk of arrhythmia with digitalis if hypokalemia develops.

Use caution with immunizations during therapy.

✔️ Contraindications
  • Systemic infections without appropriate anti-infective cover.
  • Hypersensitivity to prednisolone or formulation components.
  • Ocular herpes simplex (risk of corneal perforation).
✔️ Precautions & Warnings
  • Avoid exposure to chickenpox/measles; seek immediate medical advice if exposed.
  • An increased dose may be needed during stress (surgery, trauma, severe illness).
  • Can mask signs of infection and reduce immunity.
  • Avoid smallpox vaccination; other vaccines may be less effective or risky.
  • Monitor growth in children on long-term therapy.
✔️ Storage:

Store in a cool, dry place away from light. Keep out of children’s reach.

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Check our pricing section for Pednisol 5 | 1 Strip price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
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